It depends on the placing of the element in the periodic table.
For the far left, group 1, the most reactive element is the one
closest to the bottom. For the far right, the most reactive is the
one closest to the top.
The table follows certain trends, depending on it's placement in
the periodic table. By learning these trends, you'll be able to
tell at a glance. For example, Francium, the bottom-left most
element only ever exists for a fraction of a second; it's so
reactive, it reacts when it is created.