A statistical means of including local general information, intuitive judgment, clinical skill as learned over a long period, and similar subjective influences, in the assessment of probability, e.g. in making a diagnosis. The formula relates, for example, the conditional probability P(D/S), of a disease (D) being present when a particular sign (S) is observed, to three other probabilities: the prevalence of the disease P(D), the frequency of the sign P(S), and the probability of the sign occurring for the disease P(SD).$${\rm Pr(D\vert S) = {Pr(S\vert D) \times Pr(D)\over Pr(S)}$$


