The neonatal Fc receptor is an Fc receptor which is similar in structure to MHC class I. It was first discovered in rodents as a unique receptor capable of transporting IgG from mother's milk across the endothelium of newborn rodent's gut. Further studies revealed a similar receptor in humans. In humans, however, it is found in the placenta to help facilitate transport of mother's IgG to the growing fetus and it has also been shown to play a role in monitoring IgG turnover.
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Transmembrane receptors: immune receptors |
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Interleukins ( 2, 3, 4, 5, 6, 7, 9, 11, 12, 13, 15, 21, 23, 27)
CSF receptors (EPO, GM-CSF, G-CSF)
GH · prolactin · Oncostatin M · Leukemia inhibitory factor
common subunits ( Common gamma chain, common beta chain, gp130)
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