Inositol phosphates are a group of mono- to polyphosphorylated inositols. They play crucial roles in diverse cellular functions, such as cell growth, apoptosis, cell migration, endocytosis, and cell differentiation. The group comprises:
- inositol monophosphate
- inositol trisphosphate
- inositol pentakisphosphate
- inositol hexaphosphate
Contents |
Functions
Inositol triphosphate
Main article: Inositol triphosphate
Inositol trisphosphates act on the inositol triphosphate receptor to release calcium into the cytoplasm. Further reading: Function of calcium in humans
Other
Inositol tetra-, penta-, and hexa-phosphates have been implicated in gene expression[1] and Steger[2] (both in Science Magazine).
References
- ^ Shen X, et al. Modulation of ATP-dependent chromatin-remodeling complexes by inositol polyphosphates. Science. 2003 Jan 3;299(5603):112-4. PMID 12434013
- ^ Steger DJ, et al. Regulation of chromatin remodeling by inositol polyphosphates. Science. 2003 Jan 3;299(5603):114-6. PMID 12434012
External links
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