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Ultra violet radiation from sunlight causes Pyrimidines in DNA to bind together in a way they aren't supposed to. This binding most often occurs between two thymines creating a thymine dimer. The dimer must be cut out of the DNA strand and replaced in a process called Nucleotide Excision Repair. In the disorder Xeroderma pigmentosum (abbreviated XP) one or more of the excision repair enzymes is missing leading to extreme sensitivity to sunlight and high likelihood of skin cancer.

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Q: Abbreviation for the disease in which one of the enzymes needed to repair sunlight damsaged DNA is missing?
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