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Are there spider in Ohio that when bitten cause the skin to break down?

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The brown recluse is found there. Some staph infections also mimic a recluse spider bite as well.
ANS2: Yes, that is the mechanism of injury for all spider venom. Since they can't chew, they inject their prey with their proteolytic venom and the tissue turns into a 'bug smoothie' that they suck out. The Brown Recluse and the Black Widow spiders are found in Ohio and their venoms are particularly good at liquefying human tissue.
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What do you do if your bitten by a spider?

This question needs more information: What spider? What country? If  you are worried, see your doctor. As you seem to have time to write  this question, and wait for an answ