Best route from greenville nc to oxford Ohio?

Answer 1

1. Take U.S. 264 WEST from Greenville to U.S. 64 WEST to RALEIGH.
2. Take U.S. 64 WEST to I-540 at EXIT 423.
3. Take I-540 to I-40 to DURHAM and RALEIGH at EXITS 1B-A.
4. Exit at EXIT 1B onto I-40 WEST to DURHAM.
5. Take I-40 WEST through North Carolina to I-640 WEST TO U.S. 25W and I-75 NORTH to LEXINGTON.
6. Take I-640 WEST around Knoxville to I-275 SOUTH and I-75 NORTH to KNOXVILLE and LEXINGTON.
7. Follow signs to I-75 NORTH to LEXINGTON. Take I-75 NORTH through Tennessee and Kentucky to I-74 WEST U.S. 52 WEST and U.S. 27 NORTH to INDIANAPOLIS at EXIT 4 just past downtown Cincinnati in Ohio.
8. Take I-74/U.S. 27/52 to the continuation of U.S. 27 NORTH on COLERAIN AVE at EXIT 18.
9. Follow U.S. 27 NORTH to Oxford.