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Promethethazine is combined with codeine and sometimes Dextromethorphan that is classified as an antihistamine used to treat Allergies, motion sickness, nighttime sedation and pain reliever. it is OK to take with ibuprofen, aspirin or acetominiphine(tylenol). if Advil or aspirin upset your stomach, then OK to take with Tylenol. there are no drug interactions. this drug also treats colds and cough.

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Q: Can you take a fever reducer with promethazine?
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