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Yes, Zypan will help by supplying more acid. Zypan contains betaine hydrocloride and pancreatic enzymes. Acid reflux is caused, more than likely, by not enough stomach acid, causing the esophageal sphincter to relax and allow stomach acid to rise out of the stomach. That is why you feel the burning. I took Mylanta for many years for indigestion not knowing I needed more stomach acid instead of less. Since taking Zypan, I have not taken any OTC drugs for indigestion or acid reflux. For more information, check out the following link.

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Q: Does zypan help acid reflux
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