Identify it, cut it back and treat the base of the plant with a "Round-up" type product. [Try not to burn piles of Poison Ivy's.]
Cats
Salt
step on it.
Kill it. Kill it now.
The best way to kill someone with is to raise the dead. I know a sorcerer that could do this for you. If zombies don"t work, then that sucks.
shoot it from a distance
coffee is the best way forward.
Kill everyone....
Burn them
you can not kill rocks there not alive
No Way!
The best way to get lvl 1 clue scrolls is to kill lvl2 men or women or kill goblins lvl2.