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Many of the natives died of small pox. This helped the Spanish take over the Inca empire.

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Q: How did smallpox the disease help the spanish conquistadors defeat the natvie American population?
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What was the reason for native population in central Mexico to decrease starting in 1500?

Disease brought by Spanish conquistadors, such as smallpox. Native Americans didn't have immunity and died by the millions.


What European disease contributed to the death of more than one half of the Native American population in the 1500s?

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A disease called small pox. the Spanish conquistadors brought it over from Spain.


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The Spanish conquistadors, who brought with them diseases such as smallpox that devastated the native populations due to lack of resistance. As much as 90% of the population died due to either disease or the brutal slavery conditions imposed by the conquerors.


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What was the date smallpox was used as a biologicaal weapon?

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