if your thinking about alchemy like in Fullmetal alchemist the show, then making life would work, but the answer is no for alchemy in today's alchemy, as in making a penny turn to gold by the process of mixing chemicals.
Zed's alchemy
how to make pinocchio in littie alchemy
To get 1Up on Little Alchemy, the combination is Life + Mushroom
Life=Energy+Swamp
Swamp + energy = life
clay + life
Ash+Life
life and earth
life + ash
life + ash
life and plant
Sand+life=seed