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As the question suggests, both low and high blood pressures can lead to kidney injury (previously called "kidney failure"). Low blood pressure decreases the blood flow to the kidney, and since the kidney's function depends on adequate blood flow, it may not be able to do its job at such a low blood pressure. Consequently, the glomerular filtration rate (GFR), a measure of kidney function, may drop; a low GFR is one measure of kidney injury. If the low blood pressure persists, not only does kidney function decrease, but the kidneys can actually become damaged. Low blood flow can lead to inadequate oxygen delivery to the kidney, which can cause the cells of the kidney to fall apart, die, and leak fluid. All of these are types of so-called acute kidney injury.

High blood pressure can cause proteins to leak into the kidney inappropriately so that protein ends up in the urine (called proteinuria). Long-term proteinuria damages the filtering component of the kidney, which can rapidly lead to acute kidney injury. In addition, high blood pressure can lead to a condition called arteriolar nephrosclerosis, wherein the leaked pressures get into the walls of the kidney's blood vessels, decreasing their ability to do their job. moreover very high blood pressure would disturb the blood composition by eliminating useful components to the urinary system...therefore damaging the important function of kidney , subsequently leading to "kidney failure"

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14y ago
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14y ago

A pipe has a certain rated pressure it can withstand without damage. Blood vessels are "pipes" that transport blood. Over pressure them and they can break. Enough breakage will cause impairment of an organ.

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12y ago

Yes very much! No wonder high blood pressure is referred to as the silent killer. You see what happens is high blood pressure makes the heart work harder and over a due course of time, it can damage blood vessels throughout the body. If at all the blood vessels in the kidneys are damaged, they may stop removing wastes and extra fluid from the body .The extra fluid in the blood vessels will then raise blood pressure even more. It's a viscious cycle. In fact, high blood pressure is one of the leading causes of kidney failure. Use whatever therapy is needed including lifestyle changes to keep your blood pressure level below 130/80. And if all else fails seek medical consultation. I usually refer to a site called mediangels for any and every health related issues. A. It's convenient and B. It's got experts from around the world offering consultation on various issues.

This is not the only mechanism and not a significant one. High blood pressure injures the capillaries leading to leakage and loss of albumen as well as the damage to endothelial linings of vessels, releases factors which may cause inflammatory response, thrombosis,plaque formation; growth factors causing growth of new vessels; loss of blood and its products to interstitial or extra-vascular space and their organisation; presence of toxic substances and radicals cause further damage to cell and organ damage. One important mechanism is the ischemia with subsequent release of renin, angiotensinogens and ph and electrolyte imbalance leading to water and excreta retention and increased work for the heart and toxic environment for the cells both intra-cellularly and extra-cellularly with progressive death and loss of function of nephrons giving rise to conditions called sclerosis,nephritis, nephropathy and renal end-organ disease remediable only by dialysis and transplant.

Medicines and lifestyle changes shall still be required and play vital roles in slowing down the disease and many of the symptoms.

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9y ago

Pressure is necessary to force waste through the kidney. If it is too low, this doesn't allow for the formation of urine.
Kidney is one of the most versatile organ of your body. It takes it very offensively to have less blood supply. The rennin - angiotensin - aldosterone mechanism is activated in less blood supply. When this mechanism fails to restore the blood supply, the kidney gives away. So the kidney failure after prolonged low blood pressure is a common occurrence. But how this happens needs comments from some body expert in anatomy, physiology and pathology.

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13y ago

High blood pressure is unique in that it is both a cause and a major symptom of kidney failure

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13y ago

Yes

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12y ago

it doesn't

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Q: Is high blood pressure related to kidney failure?
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Why does a fall in pressure sometimes lead to kidney failure?

Inadequate blood flow to the kidney, as with shock, can lead to a decrease in kidney filtration and, therefore, kidney failure.


Can high blood pressure be a symptom of Chronic kidney failure?

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