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DoseBy mouth, adult and child over 5 years, 250 mg every 8 hours, dose doubled in severe infection; child, 1 month-1 year, 62.5 mg every 8 hours, dose doubled in severe infection; 1-5 years, 125 mg every 8 hours, dose doubled in severe infection

Otitis media, 500 mg every 8 hours; child 40 mg/kg daily in 3 divided doses (max. 1.5 g daily)

Pneumonia, adult over 18 years, 0.5-1 g every 8 hours

Lyme disease (see also notes above), adult and child over 5 years, 500 mg every 8 hours for 14-21 days (for 28 days in Lyme Arthritis) [unlicensed indication]; child 1 month-5 years see BNF for Children

Anthrax (treatment and post-exposure prophylaxis-see also section 5.1.12), 500 mg every 8 hours; child body-weight under 20 kg, 80 mg/kg daily in 3 divided doses, body-weight over 20 kg, adult dose

Short-course oral therapy

Dental abscess, adult over 18 years, 3 g repeated after 8 hours

Urinary-tract infections, adult over 18 years, 3 g repeated after 10-12 hours

By intramuscular injection, adult over 18 years, 500 mg every 8 hours

By intravenous injection or infusion, 500 mg every 8 hours increased to 1 g every 6 hours in severe infection; child 1 month-18 years, 20-30 mg/kg (max. 500 mg) every 8 hours; dose doubled in severe infection (max. 4 g daily)

Listerial meningitis (in combination with another antibiotic, see Table 1, section 5.1), by intravenous infusion, adult over 18 years, 2 g every 4 hours for 10-14 days; child under 18 years see BNF for Children

Endocarditis (in combination with another antibiotic if necessary, see Table 1, section 5.1), by intravenous infusion, adult over 18 years, 2 g every 6 hours, increased to 2 g every 4 hours e.g. in enterococcal endocarditis or if amoxicillin used alone; child under 18 years see BNF for Children

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Q: How much amoxicillin should an adult take?
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