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Clonazepam (Klonipin), like most benzodiazepams, is not very lethal at all. While human LD50's are indeterminate, the rat LD50 is around 4000mg/kg. Extrapolating that up for humans indicates a huge amount.

The initial dosage of clonazepam is around 1.5mg TID (three times a day), so anything over this is technically an overdose, although it most likely will just make you sleepy. But the amount required for an acute, lethal overdose is undetermined.

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Q: How much klonipin do you need to take to overdose?
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