How subtstrates and enzymes fit together?

Answer 1

There are basically two theories to suggest how enzymes and substrates fit together. They are:

1. The lock and key mechanism - this says that the structure of the substrate is exactly complimentary to the structure of the active site (i.e the region on the enzyme where the substrate fits/docks). The process is explained in terms of a lock and key analogy.

2. The induced fit mechanism - this says that the active site of the enzyme is able to change its confirmatin (i.e 3D structure) slightly in order to accomodate the substrate.

Answer 2

The substrate has to find the correct enzyme as every enzyme will fit one substrate. This is because every enzyme has it own individual active site. When the correct subatrate and enzyme join up they are a perfect match. This process is known as lock and key (becasue like a key the substrate will only fit one enzyme, a key only fits one lock). Once they have attached to each other the enzyme then squashes the substrate until it breaks. Then the two products are formed. The enzymes will work better if there the temperature and pH level are correct. Enzymes will react faster as the termperature gets hotter. But after a while it become too hot and the bonds holding the enzyme together break causing the active site to change place (meaning the substrate will not fit in). This is the same with the PH level. Most enzymes work best in a PH of about 7. Though some for example pepsin work better in a PH of 2 which is strongly acidic. (pepsin is found in your stomach)

Answer 3

a substrate is the surface an enzyme binds to but ONLY if the structure of the enzyme matches up with the structure of the substrate, they fit together exactly like a lock going into a keyhole does. the key may be able to jammed in to the lock but it's not going to unlock the door unless it's the specific key needed

Answer 4

Enzymes are proteins (and very occasionally ribosomes) that catalyse reactions. They lower the activation energy so that the reaction proceeds much, much faster.

They can achieve this in many ways:

- By coupling non-favourable reactions with other, more favourable reactions

- Bind substrates in the correct orientation

- Provide catalytically active groups

- Stabilize the transition state

Answer 5

Substrate interact with enzymes for the enzymatic conversion to product. It largely specific to its particular substrate. They interact each other with non covalent interactions such as ionic and hydrogen bonding. Once the product is formed, the enzyme would be released for next reaction.

Answer 6

Substrates bind to their enzymes at the Active Sites.

Answer 7

Enzymes interact with substrates by having the substrates fit into the activation site of an enzyme. This lowers the activation energy that is needed to do somethin