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If you are allergic to opiates in general then taking roxicet is a terrible idea, there are tests that can be done to determine if your allergic or not.

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Q: If you are allergic to codeine is it safe to take roxicet?
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When you take codeine you get serious nausea is oxycodone the same as codeine?

It is very similar. Very few people can tolerate Oxycodone when they are allergic to Codeine. The basis of most prescription pain relievers is a derivative of Codeine. Unfortunately, I am severely allergic to Codeine, and the only pain reliever I am able to tolerate is Demerol, because it is 100% synthetic. I cannot even take over-the-counter Imodium, as it is made with Codeine. They have tried Morphine, Vicodin, Lortab, all of the "-odones", all with the same results. I assume each person is different, if you feel nauseous with any of these medications, notify your Doctor, as they may be able to supplement the medication with an anti-nausea medication. Good Luck. Ree Medical Assistant