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If you introduced some drug like acid in a microscopic dose just as a sperm and egg were coming together or as soon as the brain was developing what would happen?

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Women often introduce drugs via their bloodstream, such as acid, cocaine, heroin,alcohol etc. as the sperm and egg are coming together or as the brain is developing. It is well studied. Birth defects can result and/or learning disbilites. The degree of deformity or retardation is variable.
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What would happen if two sperm fertilized one egg?

The egg would probably die, only one sperm can go into an egg. For humans and probably for all or most species, as soon as an egg is penetrated by a sperm cell, there are inst