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Is 50mg of demerol stronger than 40mg of hydrocodone? The answer to that question is Yes. First of all hydrocodone is a schedule III drug where as demerol is a schedule II narcotic. The DEA classifies narcotics, amphetamines, sedatives, hypnotics by schedules. The lower they are on the schedule list the stronger and more powerful they are. Hydrocodone comes in 2.5mg to 10mg tabs and also comes in cough syrup. Usually hydrocodone is used as a combination drug with Tylenol. Hydrocodone can generally only be taken by mouth. Generally narcotics when taken by mouth loose 25-50% of their efficacy because they have to be broken down in the GI tract before entering the blood stream. Demerol on the other hand comes in 50mg tabs for oral use, it comes in liquid form, for injections and IV administration, where it bypasses the GI tract and goes directly into the blood stream for immediate pain relief with no loss of efficacy. Demerol can also be used in an IV drip form like morphine. Hydrocodone is designed for mild to moderate pain where as demerol is designed for moderate to severe pain. A general rule of thumb is you need 10X more medication (same medication) by mouth to get the same pain relief as you do if the medication is given IV. and a shot form maybe 5X. I hope that answers your question.

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Q: How strong is 50mg of Demerol?
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