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No, aspirin is an NSAID (non-steroidal anti-inflammatory drug). It inhibits the cyclooxygenase enzyme to reduce the body's inflammation response. It also has some blood thinning effects as well.

Antihistamines, on the other hand, work by blocking the H1 histamine receptors to reduce the histamine reaction associated with Allergies. Examples are diphenhydramine (Benadryl) and doxylamine (found in Unisom and Nyquil).

They often have anticholinergic effects which produce sedation.

There are other antihistamine drugs that block H2 receptors, but those are mainly associated with reducing stomach acid production. Examples of these are: Cimetidine (Tagamet) and Ranitidine (Zantac).

No. It is what is called a NSAID (non-steroidal anti-inflammatory drug). An antihistamine acts against histamine which the body makes in response to an allergy. The allergy response is redness, itchiness, and swelling.

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Q: Can you take antihistamine and aspirin at the same time?
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