Jacksonville to Ft. Laudedale where you can pick-up the turnpike will take between 5 and 6 hours depending on your speed and # of stops. Ft. L to Northern keys is ~2 hours. The trip to Key west from Islamerada will very greatly b/c it is only a two lane road. Allow a couple hours.
Jacksonville
280 miles taking I-95.
How many miles from west palm beach using Florida turnpike to Jacksonville fl
503 miles
The Keys are 120 miles long. Jacksonville Beach to Key West is 505 miles.
Straight up (or down) I-95 It is 284 miles according to Google Maps.
It takes 10 hrs to go from Jacksonville, FL to West Virginia.
It is 313 miles from Jacksonville to Estero via I-95 South, I-4 West, and US-17 South.
It is 506 miles according to Google Maps.
305 miles taking this route:Take I-95 SOUTH from Jacksonville to I-4 WEST to ORLANDO at EXIT 260B near Daytona Beach.Take I-4 WEST to Lakeland.
West Palm Beach to Jacksonville is 284.32 miles and would take 4 hours and 21 minutes to drive. [Source: Mapquest]
598 miles