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Tricyclics, e.g. Amitriptyline and impramine, were compounds that were introduced in the 1960s to treat depression by helping boost synaptic levels of serotonin and noradrenalin. They were called 'tricyclics' because their structure contains three amine rings joined together. Tricyclics are not commonly prescribed today and have been superseded by the newer and safer 'selective serotonin reuptake inhibitors' or 'SSRIs' for short. Tricyclics are more effective in treating serious depression than SSRIs, however; so their main use today would in those cases where the patient's depression is resistant to SSRIs or other types of antidepressants

One of the older class of antidepressant. They worked by destroying a chemical in the braincalled monoamide oxidators. This enzyme prevented the good chemicals , like serontonine, norepinephrine, and dopamine , of the brain from from being able to do their job
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9y ago
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11y ago

Tricyclic antidepressants typically bind to serotonin (and, in some cases, norepinephrine) transporters to inhibit reuptake back into presynaptic neurons, which results in the net increase in levels of monoamine (serotonin and norepinephrine) in the synapse. This synaptic increase allows for more serotonin (and/or norepinephrine) to bind/rebind with postsynaptic serotonin (or norepinephrine) receptors, which upmodulates the serotonin (or norepinephrine) signal.

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13y ago
  • imipramine
  • amitriptyline
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13y ago

Some commonly used tricyclic antidepressants are amitriptyline (Elavil), desipramine (Norpramin), imipramine (Tofranil), nortriptyline (Pamelor), and protriptyline (Vivactil).

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12y ago

Tricyclic antidepressants used to treat unipolar depression may trigger rapid cycling in bipolar patients and are, therefore, not a preferred treatment option for bipolar depression

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10y ago

The function of tricyclic antidepressants are the chemicals within are used in various medicines to treat depression. The medication helps persons living with depression.

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12y ago

Lofepramine and Imipramine

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Q: What are some tricyclic antidepressants?
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What is flexerill?

tricyclic antidepressants


When were tricyclic antidepressants discovered?

Since their discovery in the 1950s, tricyclic antidepressants have been used to treat mental depression.


What is the antidote for tricyclic antidepressants?

physostigmine


What forms are tricyclic antidepressants administered in?

Tricyclic antidepressants are available only with a physician's prescription and are sold in tablet, capsule, liquid, and injectable forms


What drugs interact with tricyclic antidepressants?

Tricyclic antidepressants may interact with.other antidepressants.Central nervous system (CNS) depressants.diet pills.amphetamines.blood thinning drugs.medicine for overactive thyroid.cimetidine.blood pressure medicines.disulfiram.


What are tricyclic antidepressants named for?

Named for their three-ring chemical structure


Tricyclic antidepressants should not be given together with?

Tricyclic are a family of antidepressants that were given to people before the SSRI. Often psychiatrists prescribe a tricyclic and a newer anti-depressant usually a selective serotonin Inhibitor or a serotonin Norefenefphan selective inhibitor. Your doctor can usual decide what is safe


Does tricyclic antidepressant increase estrogen?

No. Tricyclic antidepressants primarily increase levels of serotonin and, in some cases, norepinephrine as well. If estrogen levels increase incidentally, they do so through secondary effects in the neuroendocrine system as a result of these monoamine increases.


Which antidepressant that might aggravate glaucoma as its side effect?

tricyclic antidepressants (due to its anti-muscarinic effect)


Which medications are taken for narcolepsy?

Medications include antidepressants (tricyclic antidepressants or SSRIs) treat cataplexy, hypnagogic hallucinations, sleep paralysis and stimulants (amphetamines) may increase alertness.


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Carbamazepine , phenytoin, gabapentin , baclofen, and tricyclic antidepressants may be used to ameliorate the pain of glossopharyngeal neuralgia.


What is tested for in a 10 panel test?

amphetamine barbiturates benzodiazepines cannabinoids cocaine ethanol methadone opiates PCP Tricyclic Antidepressants