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Most persons with gastrinomas secrete profound amounts of gastric acid, and almost all develop ulcers, mostly in the duodenum or stomach.
Wiki User
∙ 13y ago
Wiki User
∙ 11y agoGastrinoma is a tumor in the pancreas, the effects are abdominal pain, diarrhea, indigestion, bleeding and feeling sick with some weight loss.
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What are the symptoms of gastrinoma?
Abdominal pain is the predominant symptom of ulcer disease. About 40% of patients have diarrhea as well. In some patients, diarrhea is the primary symptom of gastrinoma.
What is a gastrinoma?
Gastrinomas are tumors associated with a rare gastroenterological disorder known as Zollinger-Ellison syndrome (ZES).
What is the prognosis for a patient with gastrinoma?
A NIH study of patients who had surgical removal of gastrinomas found that 42% were disease-free one year after surgery and 35% were disease-free at five years.
What treatment exists for patients with gastrinoma?
Therapy for gastrinomas should be individualized, since patients tend to have varying degrees of disease and symptoms. Treatment is aimed at eliminating the overproduction of gastric acid and removing the gastrin-producing tumors.
How is gastrinoma diagnosed?
Gastrinomas are usually diagnosed by a blood test that measures the level of gastrin in the blood. Patients with gastrinomas often have gastrin levels more than 200 pg/mL, which is 4-10 times higher than normal.
What is the causes of hypoacidity?
Hyperacidity, by which I presume you mean excess acid production (and is very different from a breakdown in the stomach's defensive layers) could be due to: Excess gastrin production (full stomach stimulates gastrin release/gastrinoma (gastrin secreting tumor)) Smoking Stress (histamine release which acts on gastric parietal cells) Brain injuries (vagal nerve stimulation --> ACh production ---> directly acts on parietal cells) Burns (decreased plasma volume --> increased acid production)
What are the characteristics of XX?
Gastrinomas are an integral part of the Zollinger-Ellison syndrome (ZES). In fact, ZES is also known as gastrinoma. This syndrome consists of ulcer disease in the upper gastrointestinal tract, marked increases in the secretion of gastric acid.
Why get a serum gastric level?
A serum gastrin level is ordered to determine the level of the hormone gastrin. A blood sample is used to determine the hormone level. High levels of gastrin indicate the presence a duodenal ulcer or a gastrinoma. If your doctor suspects you may have one of these conditions this could be the reason that you would get this test done.
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