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What causes third spacing?

Updated: 10/31/2022
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Wiki User

13y ago

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Third-spacing refers to a situation in which fluid shifts out of the blood into a body cavity or tissue where it is no longer available as ciculating fluid. Examples include peritonitis, the inflammation and infection of the peritoneal membranes, and burns, in which extensive inflammation of the skin and underlying tissues causes fluid to shift out of the blood, causing edema. The result of of this shift is a fluid deficit in the vascular compartment (hypervolemia) and a fluid excess in interstitial space. Until this cause is removed, fluid remains in the "third-space"--in the body but is not a functional part of the circulating fluids.

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13y ago
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Pascal Mupiwa

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2y ago
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