That's mean "From where is your friend?"
Translation: Where is your friend from?
It means: Where is Jose from?
The translation would depend on the context, i.e. who is being spoken to/about. It could mean any of these: Where are you from? Where is she from? Where is he from? Where is it from?
The phrase (someone) "es mi amigo" means that (the person) "is my friend".
It means "Where is the teacher?".
"Esto es mi amigo" translates to "This is my friend" in English.
where is your best friend from
It means: Where is Jose from?
de dónde es usted?
¿De dónde es / son / eres / sois?"de donde eres?" (where are you from?)
It means, "Where are you from?" ¿De donde es Ud.? literally means "Of where are you?" Ud. or Vd. is an accepted abbreviation of "Usted", the formal use of the word "you".
The answer depends on where Marta is from! :) De Donde es Marta of where is Marta Where is Marta From
De donde es = Where is (singular noun) from? If it were "De donde eres?" it would mean where are YOU from. Cual es su origen = What is (it's, his, her) origin. But split that sentence down the middle between the first es and the cual, because they basically mean the same thing.
¿De dónde es Penélope Cruz? --- Where is Penélope Cruz from?
esta es su amigo
It means: 'Where is Felipe (Philip) from?'
That means where is the family from
"Where is the (female) doctor from?"