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What we know so far is that the "pathogen" is not alive. It is a protein, which we called it prion. It does not have DNA or RNA. It comprised of amino acids only. It causes problems by entering the host and change the shape of the good proteins in the brain. Then the immune cells in the brain try to eat up (engulf) these prion protein but at the same time kill the brain cells. As a result, the brain become a sponge.

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Q: What does the Pathogen of Creutzfeldt-Jakob disease look like?
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