One decent piece of evidence is that the incidence of newborns with Down's increases exponentially with the age of the mother. Once a woman reaches 45 years of age the chance of her having a child with Down's becomes 1:30, as opposed to 1:1667 if the woman is 20. No correlation like this has been found in the age of the father.
The increase in the incidence of Down's with mothers age is likely because all of the eggs a female has are with her from birth. They are trapped in one of the stages of the cell cycle (prophase 1 of meiosis). The longer the woman waits before becoming pregnant the older of an egg cell she is using. These older cells have been trapped in prophase 1 for many years. This, in some way, leads to an increase in the rate of non-dysjunction events (failure of 2 chromosomes to separate) and thus, an increase in trisomy 21.
Disorders, such as Down's Syndrome, are caused by nondisjunction.
Its called disconjunction. Sometimes it is so bad that they have a miscarriage or the following happens:Trisomy (extra chromosomeso have 47 chromosomes instead of 46)Down's syndrome (andextra number 21 chromosome)Klinefelter's syndrome (males with an extra X chromosome...XXY)
Nondisjunction
Nondisjunction is the addition or deletion of an entire chromosome. The result could be autism or downs syndrome
Nondisjunction in Meiosis 2
no there r no carrier forms for triple x syndrome. this is just a nondisjunction during meiosis of gametogenesis. this can happen with either spermatogenesis or ovariogenesis
kleinfelters syndrome
Disorders, such as Down's Syndrome, are caused by nondisjunction.
Its called disconjunction. Sometimes it is so bad that they have a miscarriage or the following happens:Trisomy (extra chromosomeso have 47 chromosomes instead of 46)Down's syndrome (andextra number 21 chromosome)Klinefelter's syndrome (males with an extra X chromosome...XXY)
Nondisjunction
Nondisjunction
Nondisjunction
Jacob syndrome, 49XYY, has to occur as a result of nondisjunction in the father. The Jacob Syndrome male would have received the X chromosome from his mother, and both Y chromosomes from the father (since the Y chromosomes can not possibly have come from the mother). Jacob Syndrome can be the result of nondisjunction in meiosis.
nondisjunction
yes . it is . nondisjunction is takes place during meiosis.
Nondisjunction is the addition or deletion of an entire chromosome. The result could be autism or downs syndrome
nondisjunction