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What is an acyl anhydride?

Updated: 9/24/2023
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An acyl anhydride is a class of organic compounds with two acyl groups bonded to the same oxygen atom, which react with water to give carboxylic acids.

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Q: What is an acyl anhydride?
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What is an example of an acid anhydride?

An acid anhydride is an organic compound that has two acyl groups bound to the same oxygen atom. Usually, the acyl groups come from the same caboxylic acid, he formula for the anhydride being (RC(O))2O + H2O


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Aspirin is generally produced by the following mechanism (starting from basic materials) Phenol --(NaOH, CO2, heat)--> Sodium Salicylate (+para isomer) --(H2SO4)--> Salicylic acid --(acetic anhydride)--> acetylsalicylic acid (Aspirin) Due to the myriad of organic reactions, there are multiple possibilities at each stage. However, the above is the most efficient and common way of synthesizing Aspirin. For example, the last reaction (esterification) may be accomplished by using an acyl halide instead of an anhydride (e.g. ethanoyl/acetic chloride instead of acetic anhydride). However, the acyl halide is more costly to synthesize and more unstable to handle.


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An acyl halide is an organic compound containing an acyl functional group directly attached to a halogen.


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When was Ahmat Acyl born?

Ahmat Acyl was born in 1944.


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An acyl bromide is an organic compound containing an acyl functional group directly attached to a bromine atom.


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An acyl chloride is an organic compound containing an acyl functional group directly attached to a chlorine atom.


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An acyl fluoride is an organic compound containing an acyl functional group directly attached to a fluorine atom.


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