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What is the cigarette death toll in the United States annually?

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443,000 each year, based on the years 2000-2004, according to the Center for Disease Control.
See http://www.cdc.gov/tobacco/

Worldwide, it's about 5 million per year, killing about half of cigarette users.
Cigarettes killed about 100 million people in the twentieth century and , at current trends, are expected to kill a billion in the 21st century.
http://www.who.int/tobacco/fctc/tobacco%20factsheet%20for%20COP4.pdf
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