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A reticulate red blood cell, or reticulocyte, is an immature red blood cell. In mammals, reticulocytes do not have a nucleus. They are slightly larger and appear more blue in colour (with standard stain) than mature red blood cells.

A nucleated red blood cell is one which contains a nucleus. Mature mammalian red blood cells do not have a nucleus. In mammals, nucleated red blood cells are more immature than reticulocytes - and are not normally seen in peripheral circulation. They can be a sign of anaemia if seen on a blood smear.

Birds and reptiles have nucleated mature red blood cells.

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Q: What is the difference between a reticulate red blood cell and nucleated red blood cell?
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