What is the difference between hydrocodone and codeine?

already exists.

Would you like to merge this question into it?

already exists as an alternate of this question.

Would you like to make it the primary and merge this question into it?

exists and is an alternate of .

Hydrocodone and codeine are NOT the same chemical compound; they're two different drugs.

Codeine is the 3-methylether of morphine. It's almost inactive on it's own, and needs to be converted into morphine via the enzyme CYP2D6 in the liver to cause opioid effects, hence it's a prodrug. The Schedule 4 version of Codeine (syrups, mixed as analgesic with other drugs like Tylenol) is still a pretty weak opioid painkiller and severe pain will typically require something stronger. The Schedule 2 version is an extremely strong opiate, but isn't typically prescribed to most patients; the Schedule 4 version is.

Hydrocodone's chemical structure is similar to codeine's but not the same. It's a great deal stronger than codeine and is hence more effective in reducing severe pain. Hydrocodone also has less severe side effects, such as itching and nausea, than codeine.
+ 723 others found this useful
Thanks for the feedback!

Kristin started as your sounding board even before the House of Night series. How has her participation in the writing process changed and grown over the course of the series?

View Full Interview
In Health

What is the difference between Darvocet and hydrocodon?

  Hydrocodone is an opiate (meaning it's a derivative of opium), I believe. Darvocet is an Opiod, which means it's synthetic and made to chemically mimic the effects (espe (MORE)

Hydrocodone have codeine in it?

NO. It is a semi synthetic narcotic and a ketone of codeine, but it was synthesized as to not being codeine. It is 8 times stronger than codeine on a weight to weight bases, a (MORE)
In Health

What is the difference between Tylenol and codeine?

Tylenol is just the over the counter pain reliever. Whereas the Tylenol with codeine is that same plus a low dose of codeine which is a low level opiate, similar to a percacet (MORE)
In Legal

Codeine Drug Test Basics

If you are looking for a job in the private sector or in government there is a very good chance that you will have to undergo a drug test. It may be a urine sample, a blood te (MORE)
In Dating

The Most Common Problems That Arise in Relationships With Age Differences

Dating is hard enough; how do you deal with the issues that come with dating someone who is a few years older or younger than you? Small age differences between adult couples (MORE)

Headache: Battle of the Sexes

Men and women are biologically different. We all know hormones like estrogen and testosterone differ between the sexes, but there are many other important differences between (MORE)

The Different Variations of Pianos

You probably have some notion that there are a lot of different piano styles, but are able to name them? You're probably aware of the big piano they play at concerts and the l (MORE)

An Introductory Definition of Narcotics

The original definition of narcotics comes from the ancient Greek word "narko" which means "I benumb," referring to any psychoactive compound that induces sleep. In the United (MORE)