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The therapeutic index of drugs is the ratio between the amount of drug needed to kill 50% of the cells of the experimental animals and the dose needed for 50% of the cells to respond. The larger the therapeutic index, the safer the drug.

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6y ago
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9y ago

It is important to have the therapeutic index because that is what is used to show what is toxic to humans. This is a collection of data that is used for research.

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Q: What is the therapeutic index of drugs?
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Related questions

What does low therapeutic index mean?

Drugs with a low therapeutic index have a narrow margin of safety.


Is therapeutic index a useful measure of safety?

It is for certain drugs such as Digoxin as they have such a narrow therapeutic index. For drugs with a wide range of therapeutic index, the best measure of safety is the maximum daily dose, its effect on the patient and what other drugs it interacts with. Ask your pharmacist for specific safety questions on your specific drugs.


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What drugs appear to produce therapeutic effects by blocking receptor sites for dopamine?

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What is an acceptable therapeutic index for approval by the FDA?

There is no specific or fixed acceptable therapeutic index (TI) for FDA approval. The TI is a measure of the safety and efficacy of a drug, calculated by dividing the lethal dose in 50% of the population (LD50) by the effective dose in 50% of the population (ED50). The FDA evaluates the TI along with other factors such as the drug's intended use, benefits, risks, and overall safety profile to determine whether to approve a drug for marketing. The acceptable TI varies depending on the specific disease or condition being treated and the potential benefit of the drug.


Do therapeutic drugs work to relieve symptoms?

Type your answer here... yes


What are the common therapeutic doses of drugs?

You must include some drugs. There are many more than we can list here. A handbook of drugs is where to look.


Which drugs are administered topically for local therapeutic effects?

Drugs in this class include anestheics, anti-inflammatory drugs, antifungals, antiseptics, astringents, and others.


What are therapeutic drugs?

Form of treatment that aids in keeping the body's health maintained.


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What are antianemia drugs?

Antianemia drugs are therapeutic agents which increase either the number of red cells or the amount of hemoglobin in the blood.