What is the lock-and-key principle of enzyme action?

Answer 1

The lock is the enzyme and it's active site is where you put the key in. The key is like the substrate that comes and binds to the active site, or the key that fits into the lock.

Answer 2

The lock and key model is a basic explanation of how an enzyme works. The active site is considered the lock, and the substrate the key. When the lock and key combine, they are able to form a new substance since the active site catalyses the reaction.

This theory has since been discredited due to a more accurate model proposed. The latest model we have in Biology is known as the Induced Fit Model. Although the principle is similar to the lock and key model, the Induced Fit Model further explains how enzymes behave. When the substrate reaches the active site, the enzyme "pushes" together or changes shape so the molecule can be broken down into two parts. For example, maltase is the enzyme that metabolises maltose. When the maltose substrate lands in the active site, the enzyme changes shape so the maltose is broken into two pieces and able to be further metabolised.

Answer 3

in order to explain the mechanism of enzymes action a German chemist Emil fischer,in 184,proposed the lock and key model.According to this model both the enzymes and the substrate possess specific complementary geometric shapes that fit exactly into one another.This model explain enzyme specificity.

Answer 4

in order to explain the mechanism of enzymes action a German chemist Emil fischer,in 1894, proposed the lock and key model. According to this model both the enzymes and the substrate possess specific complementary geometric shapes that fit exactly into one another.This model explain enzyme specificity.

Molecules do have physical shapes, and in addition, they have patterns of varying positive and negative electrical charges, because some of their constituent atoms have a greater affinity for electrons than others do. The combination of the molecule's shape and its pattern of charge will make it either fit or not fit with any other molecule, much in the way that the shape of a key determines whether it does or does not fit in any given lock. Enzymes fit with very specific molecules, to perform their function.

Basically its something called the lock and key theory, each enzyme is specific to a particular substrate which mean one enzyme will only act on one particular substrate. each enzyme has what is called an active site which is where the substrate attach to the enzyme the active site will have a shape that matches that of the substrate and since the active site fits exactly to the substrate this is called a lock and key.

The lock and key is used as an analogy of enzyme catalysis in a cellular reaction. The substrate is the key and the enzyme is the lock. There will be no reaction if the key does not fit the lock. Enzymes are specific and only molecules with the correct shape can fit into the enzyme. Just like only one key can open a lock, only one type of enzyme can speed up a specific reaction. This is called the lock and key model.

Answer 5

Enzymes attach to the molecule to break down carbs. If they become too hot (during exercise or changes in our external environment) the chain distorts and so we are not able to break down carbs. Without being able to do this we are not able to produce A.T.P (energy) and we can die.