The role of the CD4 receptors in HIV is so that the virus fuses with the T helper cells.
CD4+ it is the recepetor that HIv recognize to attach with the host cell.Its the entry site of HIV in the cell.
helper T cells
HIV targets CD4+ cells in your immune system, and uses them for factories of reporduction. The CD4+ lymphocyte is the most potent killer in your immune system. By killing off these CD4+ cells, HIV can effectively render your immune system useless and leave you susceptible to many different types of infections that can be fatal.
Person with 512 cd4 count he or she HIV positive
coz CD8 and CD4 are two diffrent types of proteins .. n HIV requires cd4 to fuse for replicatin
Once the HIV virus enters the body, it seeks out specific white blood cells called CD4 T-helper cells. It than begins the process of entry and replication using the mechanism of the CD4 cells. This allows the virus to multiply and grow. In time, the HIV virus will overtake and destroy all CD4 cells which the body needs as a defense against illness. The destruction of CD4 cells makes the body vulnerable to opportunistic infections, thereby causing illness in those infected.
AIDS in the medical condition that results from infection with the HIV virus. A person can potentially live years with HIV without having AIDS.However, there are generally three things healthcare providers will look for when diagnosing AIDS:1) Viral load count--that is, how much of the HIV virus does the individual have in their body. This can be detected via a blood test.2) CD4 cell count--this is a measurement of the number of CD4 cells the person has. As the disease progresses, a person's CD4 count will drop to low levels, indicating that the immune system is failing. Generally, a CD4 count of below 200/millimeter of blood is an indicative of AIDS3) The development of opportunistic infections--Individuals whose immune system is failing will often develop infections, known as opportunistic infections. The most common opportunistic infections in AIDS patients are: Kaposi's sarcoma, Pneumocystis carinii penumonia and thrush.
The count only relates to the number of CD4 cells in a cubic millimetre of blood, not in your whole body. In the context of HIV, without access to treatment, the CD4 count slowly drops, eventually to zero. Some people who only start HIV treatment very late have a CD4 count of zero. By they this time would usually be ill with serious other infections. Even starting this late you can get a excellent response to treatment, and be back to healthy life.
An abnormally low number of CD4+ T lymphocytes is an indication of AIDS, the disease caused by HIV. Without enough CD4+ T cells, you are much more vulnerable to infection.
Well, HIV is a disease that majorly effects people in developing countries and it brakes down cells called CD4, CD4 is a cell that helps fight infections and get them out of the immune system. HIV adapts to the cell and uses it to multiply infecting the immune system. The body becomes weak and people then get so infected that AIDS comes around and can kill the person each year an amount of 34 million are infected with the HIV.
CD4
HIV
Essentially, the HIV virus disables the body's ability to defend itself. It targets white blood cells, specifically T-helper cells or CD4+ cells, and kills them. By doing this, the body slowly loses the ability to defend itself against infections.