Everyone is different , but generally oxycodone is better.
Oxycodone is stronger by about 50%, primarily because of it's greater penetration into the opiate receptors.
The Oxycodone 10/325. Not only is it stronger, but it would be better on your liver, seeing as it contains much less Acetaminophen (Tylenol) then the Hydrocodone 7.5/750.
7.5mg of hydrocodone is stronger than 5mg