0
What prevents acetylcholine from accumulating in the neuromuscular junction?
Wiki User
∙ 14y ago
The presence of an enzyme called acetylcholinesterasethat degrades acetylcholine is what prevents an accumulation of the neurotransmitter and sustained muscle contraction. Acetylcholinesterase is an enzyme that can be found within the neuromuscular junction. Thus, when a nerve impulse causes the release of acetylcholine at the neuromuscular junction, there is a critical time in which the neurotransmitter can bind to receptors on the muscle before it is degraded.
Wiki User
∙ 8y ago
Wiki User
∙ 15y agoAn enzyme called acetylcholinesterase cleaves the ester bond in acetylcholine to generate choline and acetic acid, which are no longer able to bind to acetylcholine receptors. Rapid clearance of neurotransmitters such as acetylcholine is crucial to normal nervous system operation.
Wiki User
∙ 12y agoACh effects are terminated by an enzymatic breakdown in the synaptic cleff by acetylcholinesterase.
Add your answer:
Earn +20 pts
Why is ''botox'' an effective anti-wrinkle treatment.describe its mechanism of action with reference to the neuromuscular junction?
"Botox" is actually a poison. It prevents muscle movement by preventing the nerve impulse to travel from the neuron across the neuromuscular junction and prevents the muscle from contracting. It is the toxin produced by the microbe that causes botulism.
The type of cell junction that prevents the contents of the stomach or urinary bladder from leaking into surrounding tissues?
tight junctions
How does Clostridium Perfringens attack and spread?
The mechanism for clostridium botulinum is that it prevents vesicle fusion of the neurotransmitter acetylcholine at the neuromuscular junction, where neurons connect with muscle. Acetylcholine is the molecule responsible for telling your muscle to move and botulism prevents this chemical messenger from leaving the neuron and reaching the muscle. The end results is silence, or paralysis. The tetanus toxin works in a similar way, however it prevents inhibitory chemical messages (glycine and GABA) from reaching the muscle and the end results is hyperactivity, or tetanus. Both result in paralysis.
Mention the location and function of thebesian valve.?
LOCATION -> it is situated at the junction of coronary sinus and right atrium. FUNCTION -> it prevents the regurgitation of blood into sinus during contraction of atrium.
Window layer in thin film solar cell?
Window layers are top layers in single-junction solar cell, which are made of high bandgap materials, to allow the transmittance of sunlight to the layers afterwards. It is sometimes highly doped to act as a passivation layer, which prevents surface recombination of minority carriers.
What systems do nerve agents affect?
Nerve agents typically affect the acetylcholine system by irreversibly binding to the enzyme, acetylcholinesterase. This prevents the body from catabolizing acetylcholine, resulting in an accumulation of the neurotransmitter in the synapse and neuromuscular junction.
Why is ''botox'' an effective anti-wrinkle treatment.describe its mechanism of action with reference to the neuromuscular junction?
"Botox" is actually a poison. It prevents muscle movement by preventing the nerve impulse to travel from the neuron across the neuromuscular junction and prevents the muscle from contracting. It is the toxin produced by the microbe that causes botulism.
What blocks a bonding site in muscle?
Several things do. Neuromuscular-blocking drugs block neuromuscular transmission at the neuromuscular junction causing paralysis. Quaternary ammonium muscle relaxants are quaternary ammonium salts used as drugs for muscle relaxation, most commonly in anesthesia.When a muscle is in a resting state, actin and myosin are separated. To keep actin from binding to the active site on myosin, regulatory proteins block the molecular binding sites. Tropomyosin blocks myosin binding sites on actin molecules, preventing cross-bridge formation, which prevents contraction in a muscle without nervous input.Several things do. Neuromuscular-blocking drugs block neuromuscular transmission at the neuromuscular junction causing paralysis.Quaternary ammonium muscle relaxants are quaternary ammonium salts used as drugs for muscle relaxation, most commonly in anesthesia.Tropomyosin blocks myosin binding sites on actin molecules, preventing cross-bridge formation, which prevents contraction in a muscle without nervous input.
Succinylcholine acts as a depolarizing agent that prevents repolarization of the nerve. Name a site within the neuromuscular junction that might be affected to prevent the muscle contraction?
It can act presynaptically on Nicotinic 2 receptors which increases the release of AcH potentiating the block at the motor end plate.
When may you wait in a box junction?
When oncoming traffic prevents you from turing right
What prevents fluid from seeping between epithelial cells?
Tight Junctions
What is the effect of curare on eliciting an action potential?
it is an alpha-toxin that binds to acetylcholine binding sites on the postsynaptic cell membrane, which prevents the acetylcholine from acting. Curare blocks synaptic transmission by preventing neural impulses to flow from neuron to neuron. It does allow the action potential to travel in the axon, it just doesn't pass it on to the dendrite.
Why does curare create an action potential?
Curare does NOT create an action potential. It binds to nicotinic acetylcholine receptors (which are primarily excitatory), and prevents the formation of an action potential.
The type of cell junction that prevents the contents of the stomach or urinary bladder from leaking into surrounding tissues is the?
Tight Junctions
The type of cell junction that prevents the contents of the stomach or urinary bladder from leaking into surrounding tissues?
tight junctions
Why isn't Io covered with ice?
Io is subject to intense volcanic activity, far beyond the volcanic activty on Earth. This prevents any ice from accumulating on its surface.
How does Clostridium Perfringens attack and spread?
The mechanism for clostridium botulinum is that it prevents vesicle fusion of the neurotransmitter acetylcholine at the neuromuscular junction, where neurons connect with muscle. Acetylcholine is the molecule responsible for telling your muscle to move and botulism prevents this chemical messenger from leaving the neuron and reaching the muscle. The end results is silence, or paralysis. The tetanus toxin works in a similar way, however it prevents inhibitory chemical messages (glycine and GABA) from reaching the muscle and the end results is hyperactivity, or tetanus. Both result in paralysis.
