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What does DNA translation start with?

Updated: 8/10/2023
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13y ago

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  • The small subunit of the ribosome binds to a site "upstream" (on the 5' side) of the start of the message.
  • It proceeds downstream (5' -> 3') until it encounters the start codon AUG. (The region between the mRNA cap and the AUG is known as the 5'-untranslated region [5'-UTR].)
  • Here it is joined by the large subunit and a special initiator tRNA.
  • The initiator tRNA binds to the P site (shown in pink) on the ribosome.
  • In eukaryotes, initiator tRNA carries methionine (Met). (Bacteria use a modified methionine designated fMet.)
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12y ago
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13y ago

There are two steps to protein synthesis:

1. Transcription - DNA unwinds, mRNA is made on the DNA template, the mRNA leaves the nucleus (through the nuclear pores) and goes to the ribosomes.

2. Translation - The mRNA moves along the ribosome where the information in the mRNA (codons) give the instructions for the sequence of amino acids in the protein that is being made. Once the amino acid sequence (protein, or "polypeptide") is complete, it detaches from the ribosome.

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12y ago

Translation occurs in the cytoplasm of both eukaryotic and prokaryotic cells.

It starts when a tRNA carrying a methionine attaches to a start codon.

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12y ago

Be reproducing the DNA cells

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13y ago

AUG

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Q: What does DNA translation start with?
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