You might be thinking of 1983's The Hunger which stars Catherine Deneuve as a seductive vampire (aren't they all?) and her centuries-old boyfriend (Bowie) who is about to disintegrate, so she chooses a new lover played by Susan Sarandon.
The Hunger, starring David Bowie and Catherine Deneuve. The film features a recording of Bauhaus performing Bela Lugosi is Dead.
David Bowie played an alien named Thomas Jerome Newton in the 1976 movie The Man Who Fell To Earth.
He was around the age of 38 when he made Labyrinth.
The Heartbreak Kid (2007) and David Bowies Serious Moonlight (1983). It was also used in an episode of Supernatural.
Technically since his character is a vampire of sorts, he's dead when the film begins. Spoiler Alert! . . . . . . . . . . He becomes ill. Catherine Deneuve boxes him up and puts him in the attic. But at the end of the film, the boxee's have recovered and it's Deneuve that's boxed.
Bowie's second movie was in 1976 when he appeared in "the man who fell to earth"
David Bowie
Labyrinth
Labyrinth
The Hunger, starring David Bowie and Catherine Deneuve. The film features a recording of Bauhaus performing Bela Lugosi is Dead.
David Bowie
David Bowie played an alien named Thomas Jerome Newton in the 1976 movie The Man Who Fell To Earth.
David Bowie played Jareth the Goblin King in the 1986 film Labyrinth
He was around the age of 38 when he made Labyrinth.
The Man Who Fell To Earth
Queen Bitch, by David Bowie
Just a Gigolo