Who invented electrophoresis?

Answer 1

The gel electrophoresis technique is developed by Joe Sambrook and Bill Sugden. They used agarose gel electrophoresis to separate DNA fragements. The most easily way the macromolecules through the gel porous starts with smallar molecules than larger molecules.

Answer 2

Precise information about invention of gel electrophoresis is not known. However, the first documented use of the profess was in the early 1930's (with sucrose).

In 1959, Milan Bier composed a history of the process and cites its origin in the 1800's.

Answer 3

The technique was invented by Grant Henry Lathe and Colin R Ruthven, working at Queen Charlotte's Hospital, London.[3][4] They later received the John Scott Award for this invention.[5] While Lathe and Ruthven used starch gels as the matrix, Jerker Porath and Per Flodin later introduced dextran gels;[6] other gels with size fractionation properties include agarose and polyacrylamide. A short review of these developments has appeared.[7]

There were also attempts to fractionate synthetic high polymers; however, it was not until 1964, when J. C. Moore of the Dow Chemical Company published his work on the preparation of Gel Permeation Chromatography (GPC) columns based on cross-linked polystyrene with controlled pore size,[8] that a rapid increase of research activity in this field began. It was recognized almost immediately that with proper calibration, GPC was capable to provide molar mass and molar mass distribution information for synthetic polymers. Because the latter information was difficult to obtain by other methods, GPC came rapidly into extensive use.[9]

Answer 4

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