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Why a lethal dominant genetic disease persists in the gene pool?
Wiki User
∙ 13y ago
That depends on what you mean by lethal. If you mean e.g. the gene for Huntington's disease than this is because the carrier is likely to pass on their genes before death as it only manifests later on in life. Unless the gene causes the carrier to die before they reproduce - it will stay in the gene pool. Would you kill someone because they had a genetic disorder or not let them reproduce?
Wiki User
∙ 12y ago
Wiki User
∙ 12y agoPeople who carry the DNA for the genetic disease pass the genetic DNS down to their own children.
Just because you have a gene for a genetic disease doesn't mean you have the actual disease.
Some people are cystic fibrosis "carriers" meaning they have the gene for the disease, but don't have the actual disease.
Some people have genes for genetic fatal diseases and not even know it.
They have children and pass the gene on to their children and so forth.
Wiki User
∙ 13y agoIn most cases the disease doesn't show any symptoms or doesn't incarnate until after the victim has reproduced, simple as that.
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Why are dominant genetic disorders rare in humans?
Intuitively, natural selection should eliminate these lethal genetic disorders from the population.....However, natural selection does not act on the genotype of an individual, but on the phenotype. Many of these lethal genetic disorders are the product of two "recessive alleles" that were masked in the parents with a "dominant allele."
What is dominant lethal allele?
Dominant lethal is a genetic trait. If the genome of an individual has the trait, it is expressed and makes it impossible for the individual to have descendants. Its effects cause foetal or embryonic death.
Is achondroplasia sex linked or autosomal?
It's an autosomal dominant disease. Source: http://en.wikipedia.org/wiki/Achondroplasia
A healthy individual is a carrier of a lethal allele but is unaffected by it what is the probable genotype of this individual?
N-normal l-lethal Nl so, dominant normal and recessive lethal, making him/her normal but carries a lethal allele.
Why are dominant alleles that cause lethal disorders less common that recessive alleles that cause lethal disorders?
A lethal dominant gene prohibits the organism from reproducing irregardless of the paired gene, so it is removed from the gene pool as soon as it appears. A lethal recessive gene, on the other hand, does not prevent reproduction unless it is paired with another lethal recessive, so it may be passed down through many generations before becoming paired and preventing reproduction.
How do dominant lethal alleles persist in populations even though their fitness is essentially zero?
Huntington's disease, where the lethal allele expresses itself very late in an individuals life. Persons carrying the dominant lethal allele does not become aware of the disease until after their reproductive age. Thus, they pass the lethal allele to their children without knowing and the allele persists.
What is an example of a lethal dominant mutation?
the example of lethal dominant mutation is huntington's disease.
Is Huntington's disease caused by 3 chromosomes of the 21st pair?
page 314 Huntington's disease is lethal GENETIC DISORDER caused by a rare dominant allele. It's not a chromosonal disease, it is a genetic disorder. D
Why are dominant genetic disorders rare in humans?
Intuitively, natural selection should eliminate these lethal genetic disorders from the population.....However, natural selection does not act on the genotype of an individual, but on the phenotype. Many of these lethal genetic disorders are the product of two "recessive alleles" that were masked in the parents with a "dominant allele."
What is dominant lethal allele?
Dominant lethal is a genetic trait. If the genome of an individual has the trait, it is expressed and makes it impossible for the individual to have descendants. Its effects cause foetal or embryonic death.
What is the most common lethal genetic disease in US African Americans?
Cystic fibrosis it is characterized by thick mucus in the lungs
How would the huntington disease pattern change if it was a lethal dominant at birth?
Then HD would disappear after 1 generation. No one would be alive with HD that could pass it down to their children.
What are examples of lethal genetic disorders?
This means that you have a genetic disease where as your DNA suppresses certain proteins in your body, thus either 1: giving you a deadly mutation somewhere on the body or 2: killing you I think?
Is achondroplasia sex linked or autosomal?
It's an autosomal dominant disease. Source: http://en.wikipedia.org/wiki/Achondroplasia
Is Tay Sachs disease a dominant lethal allele?
I believe it is an autosomal recessive disorder, meaning it is only apparent with a homozygous recessive genotype. But i could be wrong (i loathe biology). oh really?
Why do you not often see dominant deadly alleles?
Lethal dominant alleles normally die before obtaining the ability to reproduce.
A healthy individual is a carrier of a lethal allele but is unaffected by it what is the probable genotype of this individual?
N-normal l-lethal Nl so, dominant normal and recessive lethal, making him/her normal but carries a lethal allele.
