Mutation usually causes the entire base sequence to defect. This usually happens during the protein synthesis.
A frameshift mutation completely changes the genetic code from the point of the mutation, so the protein made as a result of the mutation would have the incorrect structure and would not function as it should.
Protein synthesis requires two steps: transcription and translationMessenger RNA (mRNA) a copy of a portion of the DNA. It carries genetic information from the gene (DNA) out of the nucleus, into the cytoplasm of the cell where it is translated to produce protein. Proteins are created by ribosomes translating mRNA into polypeptide chains. These polypeptide chains undergo PTM (Posttranslational modification) to give the mature protein.
Changing a base pair on a human chromosome (or any organism's chromosome) can range from no effect to catastrophic. The changing of a base pair -- a mutation -- can either result in a nonsense mutation, a missense mutation, or a silent mutation.A nonsense mutation changes a codon upstream of the normal stop codon into a stop codon, resulting in a truncated protein. Such proteins are non-functional and usually result in a non-viable offspring although some can survive (with serious genetic disorders).A missense mutation is just like a nonsense mutation, except the codon isn't changed into a stop codon and the protein does not terminate early. The only difference between the normal protein and the affected protein is that the affected protein will have one amino acid along the polypeptide chain that is different. The affects of such a change can change the shape of the protein entirely, seen with sickle-cell anemia.A silent mutation has no effect on the protein produced. There are only 20 amino acids, but 43 variations of four bases arranged three at a time (in other words, there are 64 different codons possible). Accordingly, more than one codon can code for the same amino acid. For example, both UAU and UAC code for the amino acid tyrosine. Imagine a point mutation replaced the U in UAU with a C making it UAC. Either way, the amino acid that will be used will be tyrosine, in no way changing the structure of the protein. For that reason, these mutations are "silent" or having no effect.
gene- coding or gene manipulationor if youre looking for the answer from novelstars ;;; MUTATION :D
it is known as mutation
Insertion mutations can affect many amino acids in the protein.An insertion mutation usually causes more defects during protein synthesis than point mutation because an insertion mutation will affect many amino acids in the protein.
Insertion mutations can affect many amino acids in the protein.An insertion mutation usually causes more defects during protein synthesis than point mutation because an insertion mutation will affect many amino acids in the protein.
Insertion mutations can affect many amino acids in the protein.An insertion mutation usually causes more defects during protein synthesis than point mutation because an insertion mutation will affect many amino acids in the protein.
Inducible: usually off for protein synthesis but can be turned on Non inducible, or REPRESSIBLE : usually on for protein synthesis but can be turned off Inducible: usually off for protein synthesis but can be turned on Non inducible, or REPRESSIBLE : usually on for protein synthesis but can be turned off
It depends. Because many amino acids have more than one codon, it may not affect the protein at all. However, if it does change the amino acid sequence, it could cause a change in the three-dimensional structure of the protein, resulting in a mutation.
DNA to RNA to protein
A protein is a topic that is vital, and that requires professional tending to regarding
A frameshift mutation completely changes the genetic code from the point of the mutation, so the protein made as a result of the mutation would have the incorrect structure and would not function as it should.
a mutation that does not affect protein production.
A Missense Mutation.It is a point mutation where the mutations alters the base sequence without changing the resulting function of the subsequent protein. This is usually when the mutation does not change the amino acid which the codon codes for.
it stops when an amino acid is missing from the diet
Usually on the rough endoplasmic reticulum.