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With chronic or severe stress, the body reacts by mounting a stress response through the stimulation of the sympathetic nervous system. This is also called the "fight or flight" response as the body arms itself to face what it perceives as danger

causeing the adrenal cortex to increase production of the anti-stress hormone cortisol.

Antidepressants calm the 'fight or flight' reaction of high cortisol levels.

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Q: Why treat high cortisol levels with anti depressants?
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