Mostly because the Medici family, who was very rich and powerful at the time, sponsored many artists like da Vinci, Brunelleschi, and Michalangelo, and without them they wouldn't have been able to create and sell so much work.
Florence is the central development of the Renaissance because it began and was a cultural movement that spanned roughly the 14th to the 17th century there. In Assassin's Creed 2, the probablity of the coordinators to create it as the center of attention was because it all simply began there.
Florence, Milan, Venice, and Genoa Florence, Milan, Venice, and Genoa
There were more than three, but three prominent Italian cities during the renaissance were Venice, Florence and Bologna,
Florence and Venice................... i think
Venice, Florence
The city most often cited as the birthplace of the Renaissance is Florence.
Florence and Venice
Florence, Milan, Mantua, Venice, Rome, Naples, Urbino, Ferrara.
The citys are Milan, Venice, and Florence.
Venice was an very influential place
there were actually three in Italy, : Florence, Venice and Rome.
Milan is the wealthiest city in Italy.
The major TRADE Cities were: Rome, Florence, Venice, Bologna, Naples and Milan.