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Absolutely. Butalbital will flag the test because it contains Benzodiazapine (Benzo). Been there, done that. Got off because it's part of one of my prescriptions - I still remember the nastygram my doctor wrote to the Navy drug testing program reaming them for questioning her treatment plan. Never heard from them about it ever again.

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15y ago
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Q: Will taking butalbital make you fail a drug test?
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