abbr. for cone-rod homeobox protein; a transcription factor protein (299 residues) that contains a homeodomain in its N-terminal region and is expressed specifically in developing and mature photoreceptor cells of the retina. It regulates expression of the genes for rhodopsin and other photoreceptor-specific proteins. Mutations in the gene at 19q13.3 result in a form of blindness called Leber's congenital amaurosis.
| CRP, CRM-positive, CRM | |
| CRY, CS, CSD |
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