Tretinoin - Information from Answers.com
Tretinoin is the acid form of vitamin A and is also known as all-trans retinoic acid or ATRA. It is a ... ATRA acts on PML-RAR to lift this block, causing the immature ...
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Retinoic acid - Information from Answers.com
For all-trans-retinoic acid as a drug, see Tretinoin. For 9-cis-retinoic acid as a drug, see Alitretinoin. For 13-cis-retinoic acid as a drug, see Isotretinoin.
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Retinol - Information from Answers.com
Tretinoin, under the alternative name of all-trans retinoic acid (ATRA), is used as chemotherapy for acute promyelocytic leukemia, a subtype of acute ...
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CYP26A1 - Information from Answers.com
This endoplasmic reticulum protein acts on retinoids, including all-trans-retinoic acid (RA), with both 4-hydroxylation and 18-hydroxylation activities. This enzyme ...
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Retinoic acid receptor gamma - Information from Answers.com
"Crystal structure of the RAR-gamma ligand-binding domain bound to all-trans retinoic acid". Nature 378 (6558): 681–9. doi:10.1038/378681a0. PMID 7501014.
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Acute promyelocytic leukemia - Information from Answers.com
APL is unique among myeloid leukemias due to its sensitivity to all-trans retinoic acid (ATRA), a derivative of vitamin A. Treatment with ATRA dissociates the ...
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Retinoic acid syndrome - Information from Answers.com
"Clinical and biological features of acute promyelocytic leukemia patients developing retinoic acid syndrome during induction treatment with all-trans retinoic ...
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Retinoic acid receptor - Information from Answers.com
The retinoic acid receptor (RAR) is a type of nuclear receptor that is activated by both all-trans retinoic acid and 9-cis retinoic acid. There are three retinoic acid ...
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CYP26B1 - Information from Answers.com
"Identification of the human cytochrome P450, P450RAI-2, which is predominantly expressed in the adult cerebellum and is responsible for all-trans- retinoic acid ...
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