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| 11-Deoxycortisol | |
|---|---|
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| IUPAC name |
17,21-Dihydroxypregn-4-ene-3,20-dione
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| Identifiers | |
| CAS number | 152-58-9  |
| PubChem | 9050 |
| MeSH | 11-Deoxycortisol |
| SMILES |
O=C1CC[C@@]2(C)C(CC[C@]3([H])M[C@@]([H])
2CC[C@@]4(C)[C@]([H])3CC[C@@](O)4C(CO)=O)=C1 |
| Properties | |
| Molecular formula | C21H30O4 |
| Molar mass | 346.461 |
| Melting point |
215 °C |
| (what is this?) (verify) Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) |
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| Infobox references | |
11-Deoxycortisol (or cortodoxone) is a steroid, and an immediate precursor to the production of cortisol. It functions as a mineralocorticoid, though is less potent than cortisol. It can be synthesized from 17-hydroxyprogesterone. In 11-beta-hydroxylase deficiency, 11-deoxycortisol levels increase dramatically, causing hypertension (as opposed to 21-alpha-hydroxylase deficiency, in which patients have hypotension from a lack of mineralocorticoids).
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