MT-RNR1
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MT-RNR1
| mitochondrially encoded 12S RNA | |
|---|---|
| Identifiers | |
| Symbol | MT-RNR1 |
| Alt. symbols | MTRNR1 |
| Entrez | 4549 |
| HUGO | 7470 |
| Other data | |
| Locus | Chr. MT [1] |
Mitochondrially encoded 12S RNA (often abbreviated as 12S) is a 959 nt long mitochondrial ribosomal RNA (rRNA). In humans, 12S is encoded by the MTRNR1 gene.
All animal mitochondria genomes contain 37 genes, 2 rRNA, 22 tRNA and 13 mRNA. These are very useful in phylogenetic studies, in particular the 12S and 16S rRNAs.
Mutations in the MTRNR1 gene may be associated with hearing loss.[1]
External links
References
- ^ Ballana E, Morales E, Rabionet R, et al. (March 2006). "Mitochondrial 12S rRNA gene mutations affect RNA secondary structure and lead to variable penetrance in hearing impairment". Biochem. Biophys. Res. Commun. 341 (4): 950–7. doi:10.1016/j.bbrc.2006.01.049. PMID 16458854. http://linkinghub.elsevier.com/retrieve/pii/S0006-291X(06)00086-6.
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