2,3-Oxidosqualene

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2,3-Oxidosqualene

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2,3-Oxidosqualene
Identifiers
CAS number 7200-26-2
PubChem 5366020
ChemSpider 4517951 YesY
MeSH 2,3-oxidosqualene
Jmol-3D images Image 1
Image 2
Properties
Molecular formula C30H50O
Molar mass 426.717 g/mol
 YesY (verify) (what is: YesY/N?)
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

2,3-(S) Oxidosqualene ((S)-2,3-epoxysqualene) is an intermediate in the synthesis of the membrane sterol precursors lanosterol and cycloartenol, as well as saponins. It is formed from squalene by squalene monooxygenase. 2,3 oxidosqualene is the substrate of various oxidosqualene cyclases, including lanosterol synthase, which produces lanosterol, a precursor to cholesterol.[1]

2,3-(R) Oxidosqualene is an inhibitor of lanosterol synthase.

References

  1. ^ Abe I. (2007). "Enzymatic synthesis of cyclic triterpenes". Natural Products Reports 24 (6): 1311–31. doi:10.1039/b616857b. PMID 18033581. 



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