Butyltolylquinuclidine
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Butyltolylquinuclidine
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| Systematic (IUPAC) name | |
| (2R,3S,4S)-2-butyl-3-p-tolylquinuclidine | |
| Clinical data | |
| Pregnancy cat. | ? |
| Legal status | Legal |
| Identifiers | |
| ATC code | ? |
| PubChem | CID 9903250 |
| Chemical data | |
| Formula | C18H27N |
| Mol. mass | 257.414 g/mol |
| SMILES | eMolecules & PubChem |
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2-Butyl-3-(p-tolyl)quinuclidine (BTQ) is a stimulant DRI.[1] It is one of a number of substituted quinuclidine derivatives developed as potential medications for the treatment of cocaine abuse,[2] and produces similar effects to cocaine in animal studies, although milder and longer lasting.
References
- ^ Sakamuri, S.; Enyedy, I. J.; Zaman, W. A.; Tella, S. R.; Kozikowski, A. P.; Flippen-Anderson, J. L.; Farkas, T.; Johnson, K. M. et al (2003). "2,3-Disubstituted quinuclidines as a novel class of dopamine transporter inhibitors". Bioorganic & medicinal chemistry 11 (6): 1123–1136. doi:10.1016/S0968-0896(02)00450-9. PMID 12614900.
- ^ Enyedy, I. J.; Sakamuri, S.; Zaman, W. A.; Johnson, K. M.; Wang, S. (2003). "Pharmacophore-based discovery of substituted pyridines as novel dopamine transporter inhibitors". Bioorganic & medicinal chemistry letters 13 (3): 513–517. doi:10.1016/S0960-894X(02)00943-5. PMID 12565962.
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